I don’t normally review products but I felt this needed it! My 13 week old puppy has been sick every car journey (5) we have been on, and has recently been struggling with separation anxiety especially at night time. In desperation I bought this today, even after seeing some one star reviews I thought “it may not work but it’s worth a try”. So I bought the mini refill bottle just in case it was a dud. But to my excitement and relief, our puppy slept in the car (no throw up) and has settled straight back into his normal bedtime routine with no issues! It may not work for every animal but it’s worth a try for a happier pet!