I didn’t buy this on Amazon but have come to buy the diffuser with the same spray because when I use the bandana with a spray of the Pet Remedy stuff, she really does calm down. In fact, she’s gone to sleep within about fifteen minutes every time. You do need to reapply every time you use it. It could be a coincidence but I’ve used it about four times now and each time she’s totally chilled. This is why I’ve come for the diffuser – I’ve been using the Adaptil one and not sure it actually does much, whereas I’ve got a good feeling this really helps her.